Publication Type |
J |
Authors |
Chumkaew, P; Kato, S; Chantrapromma, K |
Author Full Name |
Chumkaew, P; Kato, S; Chantrapromma, K |
Title |
A new triterpenoid ester from the fruits of Bruguiera parviflora |
Source |
CHEMICAL & PHARMACEUTICAL BULLETIN |
Language |
English |
Document Type |
Article |
Author Keywords |
Bruguiera parviflora; rhizophoraceae; triterpenoid ester; antimalarial |
Keywords Plus |
DIOSPYROS-MARITIMA; CHEMICAL-SHIFTS; LUPANE; C-13; H-1; NMR |
Abstract |
A new lupane caffeoyl ester (1), 3-(Z)-caffeoyllupeol, together with five known triterpenoids, lupeol caffeate (2), 3-(Z)-coumaroyllupeol (3), dioslupecin A (4), lupeol (5), and lupenone (6), were isolated from the fruits of Bruguiera parviflora. Their structures were elucidated by spectroscopic methods. Compound 1 exhibited antimalarial activity with an EC50 value of 8.6 mug/ml, but compound 2 was inactive. |
Author Address |
Walailak Univ, Sch Sci, Nakhon Si Thammarat 80160, Taiwan; Seikei Univ, Fac Engn, Dept Appl Chem, Musashino, Tokyo 1808633, Japan |
Reprint Address |
Chantrapromma, K (reprint author), Walailak Univ, Sch Sci, Nakhon Si Thammarat 80160, Taiwan. |
E-mail Address |
ckan@wu.ac.th |
Cited References |
Alvarenga N, 2000, FITOTERAPIA, V71, P719, DOI 10.1016/S0367-326X(00)00217-3; AMMANN W, 1982, ORG MAGN RESONANCE, V20, P260, DOI 10.1002/mrc.1270200414; BOONYAPRAPHAT N, 1998, THAI MED PLANTS, V2, P157; Chang CI, 1998, CHEM PHARM BULL, V46, P1627; CHANTRAPROMMA K, 2004, ACTA CRYSTALLOGR E, V60, P312; Chumkaew P, 2003, J NAT PROD, V66, P540, DOI 10.1021/np0204489; DESJARDINS RE, 1979, ANTIMICROB AGENTS CH, V16, P710; Kuo YH, 1997, PLANTA MED, V63, P363, DOI 10.1055/s-2006-957703; Laphookhieo S, 2004, PHYTOCHEMISTRY, V65, P507, DOI 10.1016/j.phytochem.2003.10.019; Pereira FBM, 1996, NAT PROD LETT, V8, P97, DOI 10.1080/10575639608043247; REYNOLDS WF, 1986, TETRAHEDRON, V42, P3419, DOI 10.1016/S0040-4020(01)87309-9; TRAGER W, 1976, SCIENCE, V193, P673, DOI 10.1126/science.781840 |
Cited Reference Count |
12 |
Times Cited |
14 |
Total Times Cited Count (WoS, BCI, and CSCD) |
15 |
Publisher |
PHARMACEUTICAL SOC JAPAN |
Publisher City |
TOKYO |
Publisher Address |
2-12-15 SHIBUYA, SHIBUYA-KU, TOKYO, 150-0002, JAPAN |
ISSN |
0009-2363 |
29-Character Source Abbreviation |
CHEM PHARM BULL |
ISO Source Abbreviation |
Chem. Pharm. Bull. |
Publication Date |
JAN |
Year Published |
2005 |
Volume |
53 |
Issue |
1 |
Beginning Page |
95 |
Ending Page |
96 |
Digital Object Identifier (DOI) |
10.1248/cpb.53.95
|
Page Count |
2 |
Web of Science Category |
Chemistry, Medicinal; Chemistry, Multidisciplinary; Pharmacology & Pharmacy |
Subject Category |
Pharmacology & Pharmacy; Chemistry |
Document Delivery Number |
887TS |
Unique Article Identifier |
WOS:000226329000020
|